John O'Shea
Physician and Immunologist, National Institutes of Health
Thursday, April 28
7:00 p.m.
Hepburn Auditorium

"Lessons from Rare Diseases: Scientific Insights and New Drugs"

Dr. O'Shea will be discussing how patients with rare primary immunodeficiencies have taught us fundamental lessons about cell signaling and how this, in turn, has led to the development of a new class of immunomodulatory drugs.

Dr. John O'Shea has been a physician and immunologist at the National Institutes of Health for the last 27 years. He has authored more than 200 peer-reviewed articles, which have been published in the most prestigious scientific journals, including Nature, Science, Cell, etc. He is a recognized authority how cytokines regulate immunity. Dr. O'Shea has made fundamental discoveries regarding the molecular basis for cytokine signaling, the pathogenesis of primary immunodeficiencies and the genetic basis of autoinflammatory disorders. Dr. O'Shea was awarded a US patent related to generating Janus family kinase inhibitors as a new class of immunosuppressive drugs.