Biology and Psychology Faculty Members Present at Nanotoxicology Conference

Three St. Lawrence University faculty members recently presented their research findings at the 8th International Nanotoxicology Congress, held June 1st to June 4th 2016 in Boston, Massachusetts. Drs. Bill DeCoteau (Psychology), Ana Estevez (Biology and Psychology) and Kari Heckman (Biology) presented their research findings related to the use of antioxidant cerium oxide nanoparticles (also known as ceria or nanoceria) in both in vitro and in vivo studies. The titles and authors of each abstract are indicated below. Names with (*) indicate SLU undergraduate students who contributed to the work. Other collaborators included Joseph Erlichman from St. Lawrence University (Biology); James Leiter from Geisel School of Medicine at Dartmouth College; Brad Stadler and Bonnie Hays-Erlichman from Cerion, LLC in Rochester, NY.

According to the organizers of the meeting, “the objective of this conference is to bring together scientists from academia, industry, government agencies, and non-governmental organizations to present current research findings, focus their respective talents and expertise, and initiate new collaborations in an effort to ensure the safe implementation of nanotechnology.” Toward this end,  these three SLU faculty members also participated in a workshop organized by Dr. Robert Yokel from the University of Kentucky titled ‘Nanoceria:  Benefits and Risks”  where they gave 5-10 minute oral presentations of their work. The goal of this workshop was to promote scientific dialogue regarding the myriad of beneficial and adverse effects that have been reported for the various types of nanoceria studied.

Abstract titles and authors of the SLU presentations at the 8th International Nanotoxicology Congress:

Cerium oxide nanoparticles preserve muscle function and increase longevity in the SOD1G93A mouse model of amyotrophic lateral sclerosis – William DeCoteau, Karin Heckman, Ana Estevez, *Paige Studlack, *Jennifer Clauss, *Elizabeth Nichols, *Jennifer Lipps, *Matthew Parker, Bonnie Hays-Erlichman, James Leiter, Joseph Erlichman

Measurement of catalase and oxidase activity of custom-synthesized cerium oxide nanoparticles and assessment of their antioxidant effectiveness in a mouse hippocampal brain slice model of ischemia – Ana Y. Estevez, Bonnie Hays-Erlichman, *Jenna Buckleitner, *Taren McGray, *Sierra Miller, Brad Stadler, Joseph Erlichman

Subcutaneous cerium oxide nanoparticle delivery affords similar protection as intravenous delivery in a murine model of multiple sclerosis – Karin Heckman, William E. DeCoteau, *Christopher Payton, *Stephanie Vangellow, *Colby Nadeau, *Mark Provost, *Hillary Baynham, Bonnie Hays-Erlichman, Joseph Erlichman